Table 2.
Baseline characteristics of participants stratified by status regarding delayed graft function (DGF).
| Characteristics | Without DGF | With DGF | p-Value |
|---|---|---|---|
| Number (no.) of patients | 175 | 64 | |
| Recipient demographics | |||
| Age [years] | 50 ± 14 | 56 ± 13 | 0.003 |
| Female, no. (%) | 61 (34.9) | 14 (21.9) | 0.079 |
| Body-mass index [kg/m2] | 24.5 ± 4.4 | 27.8 ± 5.2 | <0.001 |
| Diabetes, no. (%) | 30 (17.1) | 18 (28.1) | 0.090 |
| Hypertension, no. (%) | 141 (80.6) | 53 (82.8) | 0.837 |
| Cardiovascular disease, no. (%) | 45 (25.7) | 34 (53.1) | <0.001 |
| Dialysis vintage [days] | 1321 ± 1331 | 2208 ± 1456 | <0.001 |
| Preemptive transplant, no. (%) | 28 (16.0) | 1 (1.6) | <0.001 |
| Pretransplant sUMOD [ng/mL] | 18.3 ± 26.8 | 5.9 ± 6.4 | <0.001 |
| Recipient laboratory measures on postoperative Day 1 (POD1) | |||
| sUMOD [ng/mL] | 51.7 ± 50.3 | 54.0 ± 50.4 | 0.747 |
| Serum creatinine [mg/dL] | 5.6 ± 2.2 | 7.1 ± 2.4 | <0.001 |
| Hemoglobin [g/dL] | 10.3 ± 1.6 | 10.4 ± 1.8 | 0.687 |
| Leucocyte count [G/L] | 11.5 ± 4.2 | 12.0 ± 4.2 | 0.479 |
| C-reactive protein [mg/dL] | 3.5 ± 2.6 | 3.2 ± 1.3 | 0.585 |
| Sodium [mmol/L] | 141 ± 4 | 139 ± 5 | 0.005 |
| Potassium [mmol/L] | 4.7 ± 0.7 | 5.4 ± 0.6 | <0.001 |
| Donor characteristics | |||
| Age [years] | 52 ± 15 | 57 ± 15 | 0.021 |
| Female, no. (%) | 96 (54.9) | 22 (34.4) | 0.008 |
| Body-mass index [kg/m2] | 25.8 ± 3.7 | 28.1 ± 5.5 | <0.001 |
| Diabetes, no. (%) | <0.001 | ||
| No | 131 (74.9) | 35 (54.7) | |
| Yes | 5 (2.9) | 10 (15.6) | |
| Unknown | 39 (22.3) | 19 (29.7) | |
| Hypertension, no. (%) | 0.209 | ||
| No | 93 (53.1) | 26 (40.6) | |
| Yes | 55 (31.4) | 24 (37.5) | |
| Unknown | 27 (15.4) | 14 (21.9) | |
| Serum creatinine [mg/dL] | 1.0 ± 0.6 | 1.1 ± 0.9 | 0.057 |
| Expanded criteria donor, no (%) | 64 (36.6) | 33 (51.6) | 0.052 |
| Transplant related variables | |||
| Living donation, no. (%) | 79 (45.1) | 11 (17.2) | <0.001 |
| Cold ischemic time [hours] | 7.2 ± 6.0 | 9.9 ± 5.5 | 0.002 |
| Warm ischemic time [minutes] | 24 ± 12 | 29 ± 14 | 0.006 |
| Primary non-function, no. (%) | 0 (0) | 8 (12.5) | <0.001 |
| No. of HLA-mismatches | 3 ± 2 | 3 ± 2 | 0.650 |
Continuous variables presented as means ± standard deviation, categorical variables presented in percentage of referring population. The p-value will compare recipients with DGF and without DGF calculated by parametric testing. sUMOD, serum uromodulin.