Figure 5.

Transcellular (endothelial or epithelial) electrical resistivity (TEER) measurements on barrier models expressing different tightness: (a) bEnd.3 cells represent a model with low barrier tightness, (b) the Caco-2 intestinal cell line serves as a tight epithelial monolayer, and (c) the Bioni010-C derived human endothelial cells express exceptionally tight barrier properties. Data are shown as means ± SEM of one individual passage with 12 individual permeable supports (n = 1, total N = 12) for Caco-2 and Bioni010-C derived endothelial cells, and one individual passage with 24 individual permeable supports (n = 1, total N = 24) for bEnd-3 cells. Statistical analysis one-way ANOVA analysis and Tukey’s multiple comparison test; * p < 0.05, *** p < 0.001.