Table 4.
Hazard ratios of TNM-8T and TNM-8 for cancer-related death.
| Alternative Grouping | TNM-8T | ||||||
|---|---|---|---|---|---|---|---|
| Cancer-Related Death | Unadjusted | Adjusted * | |||||
| Events/Total (%) | 10-y CSS | 15-y CSS | HR (95% CI) | p-Value | HR (95% CI) | p-Value | |
| TNM-8T stage 1 | 4/313 (1.3) | 98.7 | 98.7 | 1.00 (reference) | <0.001 | 1.00 (reference) | <0.001 |
| TNM-8T stage 2 | 3/31 (9.7) | 93.5 | 90.3 | 8.05 (1.80–35.97) | 0.006 | 10.62 (2.41–46.71) | 0.002 |
| TNM-8T stage 3 | 5/22 (22.7) | 77.3 | 77.3 | 21.37 (5.74–79.59) | <0.001 | 18.57 (5.02–68.70) | <0.001 |
| TNM-8T stage 4 | 15/27 (55.6) | 63.0 | 44.1 | 56.40 (18.67–170.36) | <0.001 | 62.87 (20.66–191.29) | <0.001 |
| AJCC Stage | TNM-8 | ||||||
| Cancer-Related Death | Unadjusted | Adjusted * | |||||
| Events/Total (%) | 10-y CSS | 15-y CSS | HR (95% CI) | p -Value | HR (95% CI) | p -Value | |
| TNM-8 stage I | 8/329 (2.4) | 97.6 | 97.6 | 1.00 (reference) | <0.001 | 1.00 (reference) | <0.001 |
| TNM-8 stage II | 11/48 (22.9) | 85.4 | 76.3 | 10.43 (4.19–25.93) | <0.001 | 13.20 (5.08–34.30) | <0.001 |
| TNM-8 stage III | 4/9 (44.4) | 77.8 | 55.6 | 20.68 (6.21–68.84) | <0.001 | 26.99 (8.06–90.42) | <0.001 |
| TNM-8 stage IV | 4/7 (57.1) | 42.9 | 42.9 | 38.24 (11.44–127.75) | <0.001 | 26.39 (7.84–88.79) | <0.001 |
TNM-8, AJCC tumor-node-metastasis staging system 8th edition; y, year; CSS, cancer-specific survival; HR, hazard ratio; CI, confidence interval. * Cox model adjusted for sex and histological type.