Table 1.
Factors/Subjects | IL-1α | IL-4 | IL-6 | IL-7 | IL-8 | IL-10 | IL-12 | Ki 67 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
E | CT | E | CT | E | CT | E | CT | E | CT | E | CT | E | CT | E | CT | |
1 | ++ | +++ | ++ | ++/+++ | ++ | +++ | ++ | +++ | ++ | +++ | ++ | +++ | ++/+++ | +++ | + | + |
2 | +++ | +++ | ++ | ++/+++ | ++ | ++/+++ | + | ++ | ++ | ++ | +++ | +++ | ++ | +++ | +/++ | + |
3 | ++ | ++ | + | ++ | + | +++ | ++ | +++ | +/++ | ++ | ++ | +++ | + | +++ | ++ | + |
4 | 0/+ | ++ | + | ++ | ++ | +++ | ++ | ++ | ++ | ++ | ++/+++ | +++ | ++/+++ | +++ | 0/+ | 0/+ |
5 | 0/+ | +/++ | + | 0/+ | 0 | + | ++ | 0/+ | ||||||||
6 | + | +/++ | + | + | + | +/++ | + | ++/+++ | 0/+ | + | + | + | ++ | +++ | 0 | + |
7 | +/++ | ++/+++ | +/++ | +++ | + | +++ | +/++ | +++ | 0 | + | 0 | 0/+ | ++ | ++/+++ | ++ | + |
8 | ++ | ++ | + | ++ | +/++ | ++/+++ | +/++ | ++ | + | + | +/++ | +/++ | +++ | ++ | 0 | 0 |
9 | + | + | ++ | + | + | + | + | 0 | ||||||||
10 | + | + | + | ++/+++ | + | ++/+++ | + | ++/+++ | 0 | + | + | +/++ | ++ | +++ | ++ | + |
11 | 0/+ | + | + | ++/+++ | ++ | +++ | +/++ | +++ | + | +/++ | +/++ | ++/+++ | ++ | +++ | +/++ | ++/+++ |
12 | 0/+ | +/++ | ++ | ++/+++ | +/++ | ++/+++ | +/++ | ++ | + | + | ++ | ++ | +++ | ++++ | ++ | ++ |
Average | +/++ | ++ | +/++ | ++ | +/++ | ++/+++ | +/++ | ++ | + | +/++ | +/++ | ++ | ++ | +++ | + | + |
Control | ++/+++ | 0/+ | +++ | +/++ | +++ | + | +++ | +/++ | +++/++++ | + | ++++ | ++ | +++ | + | +/++ | 0/+ |
Significant Difference (p-value) | 0.001 | <0.001 | <0.001 | 0.014 | <0.001 | <0.001 | <0.001 | 0.006 | <0.001 | 0.028 | <0.001 | 0.811 | 0.002 | <0.001 | 0.309 | 0.073 |
Abbreviations: E—epithelium; CT—connective tissue; Ki 67—proliferation marker; IL-1α —interleukin 1 alpha; IL-4—interleukin 4; IL-6—interleukin 6; IL-7—interleukin 7; IL-8—interleukin 8; IL-10—interleukin 10; IL-12—interleukin 12; 0/+—occasional positive structures, +—few positive structures, +/++—few to moderate number of positive structures, ++—moderate number of positive structures, ++/+++—moderate to numerous positive structures, +++—numerous positive cells, +++/++++—numerous to abundance of structures, ++++—abundance of positive structures in the visual field.