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Robust URA network induced by levothyroxine treatment of mouse cerebrocortical cultures. Dashed orange lines signify activation (loss of inhibition) and red symbols signify upregulated genes with the Neuron Screen Z-score and adjusted p-value (p-adj) (<0.05) appearing directly below each symbol. The upstream regulator DIO3 is blue, indicating downregulation based on the C4R drug screen data.
