Table 2.
Body mass index, weight change, and 5 and 10% weight change from baseline to 6-month follow-up in patients with obesity exposed and not exposed (controls) to COVID-19 lockdown. Data from completer and intention-to-treat analysis. For repeated measure ANOVA: Mauchly’s sphericity tests were >0.05. Sphericity was assumed.
| Completer Analysis | ||||||||
|---|---|---|---|---|---|---|---|---|
| Admission | Discharge | 6-Month Follow-Up | ||||||
| Lockdown Patients (n = 71) | Control Patients (n = 77) | Lockdown Patients (n = 71) | Control Patients (n = 77) | Lockdown Patients (n = 71) | Control Patients (n = 77) | Repeated-Measures ANOVA | ||
| Time | TimeXGroup | |||||||
| Bodyweight in kg, mean (SD) | 111.7 (22.9) | 117.0 (22.2) | 106.5 (21.7) | 111.8 (21.1) | 101.1 (22.0) | 101.6 (19.7) | <0.001 | 0.002 |
| Body mass index in kg/m2, mean (SD) | 40.9 (7.4) | 43.2 (6.8) | 39.1 (7.1) | 41.3 (6.6) | 37.0 (7.2) | 37.6 (6.6) | <0.001 | 0.002 |
| t-test; p-value discharge | t-test; p-value 6-month follow-up | |||||||
| Weight loss from admission in kg, mean (SD) | -- | -- | 5.2 (3.5) | 5.2 (2.8) | 10.6 (9.2) | 15.3 (9.3) | 0.16; 0.872 | 3.09; 0.002 |
| Percentage weight loss from admission, mean (SD) | -- | -- | 4.6 (3.1) | 4.3 (2.0) | 9.4 (7.5) | 13.0 (7.1) | 0.65; 0.514 | 2.94; 0.004 |
| Chi-squared test; p-value discharge | Chi-squared test; p-value 6-month follow-up | |||||||
| ≥5% weight loss from admission, n (%) | -- | -- | 20 (28.2%) | 25 (32.5%) | 51 (71.8%) | 68 (88.3%) | 0.32; 0.570 | 6.37; 0.012 |
| ≥10% weight loss from admission, n (%) | -- | -- | 1 (1.4%) | 1 (1.3%) | 30 (42.3%) | 47 (61.0%) | 0.003; 0.954 | 5.22; 0.022 |
| Intention-to-Treat Analysis | ||||||||
| Admission | Discharge | 6-Month Follow-Up | Repeated-Measures ANOVA | |||||
| Time | TimeXGroup | |||||||
| Lockdown Patients (n = 129) | Control Patients (n = 129) | Lockdown Patients (n = 129) | Control Patients (n = 129) | Lockdown Patients (n = 129) | Control Patients (n = 129) | |||
| Bodyweight in kg, mean (SD) | 112.5 (23.0) | 115.5 (24.7) | 107.4 (21.8) | 110.5 (23.4) | 101.3 (22.6) | 101.2 (22.4) | <0.001 | <0.001 |
| Body mass index in kg/m2, mean (SD) | 41.6 (8.2) | 42.2 (8.1) | 39.9 (7.9) | 40.4 (7.7) | 37.5 (8.3) | 37.1 (7.8) | <0.001 | <0.001 |
| t-test; p-value discharge | t-test; p-value 6-month follow-up | |||||||
| Weight loss from admission in kg, mean (SD) | -- | -- | 5.06 (2.9) | 5.07 (2.8) | 11.1 (10.0) | 14.4 (10.2) | 0.12; 0.908 | 8.45; <0.001 |
| Percentage weight loss from admission, mean (SD) | -- | -- | 4.5 (2.4) | 4.3 (2.1) | 9.9 (8.6) | 12.3 (8.2) | 1.88; 0.060 | 7.36; <0.001 |
| Chi-squared test; p-value discharge | Chi-squared test; p-value 6-month follow-up | |||||||
| ≥5% weight loss from admission, n (%) | -- | -- | 37 (28.7%) | 42 (32.6%) | 92 (71.3%) | 106 (82.2%) | 5.02; 0.025 | 44.6; <0.001 |
| ≥10% weight loss from admission, n (%) | -- | -- | 1 (0.8%) | 1 (0.8%) | 59 (45.8%) | 76 (58.9%) | -- | 48.6; <0.001 |