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. 2021 Jun 12;13(12):2950. doi: 10.3390/cancers13122950

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Kaplan–Meier survival curves according to V-gene usage in anti-PD-1 treated NSCLC patients. (a,b) Progression-free survival (PFS) and overall survival (OS) curves in terms of PRE TRBV6-5 frequency. (c,d) PFS and OS curves in terms of PRE TRBV20-1 frequency. (e,f) PFS and OS curves in terms of FR TRBV20-1 frequency. The median frequency values were used as cutoff values (2.53% for PRE TRBV6-5, 9.14% for PRE TRBV20-1, and 9.02% for FR TRBV20-1, respectively). PRE: pretreatment, FR: first response assessment, p-values were obtained using the log-rank test.