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MIC values of TMP and compounds 1a and 1b in combination with SMX (1:20) as well as colistin in P. aeruginosa PAO1 in the presence or absence of the efflux pump inhibitor PAßN (20 µg/mL).
| Antimicrobial | MIC (µM) | |
|---|---|---|
| With PAßN | Without PAßN | |
| TMP (SMX) | 1.72 (39.48) | 27.56 (631.71) |
| 1a (SMX) | 5.01 (157.93) | 80.10 (2526.86) |
| 1b (SMX) | 2.05 (78.96) | 32.76 (1263.43) |
| Colistin | 1.73 | 1.73 |
