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. 2021 Jun 11;22(12):6298. doi: 10.3390/ijms22126298

Figure 5.

Figure 5

5xFAD somatosensory cortex pyramidal cells display unaltered intrinsic electrophysiological properties and firing behavior. (a) Example traces of action potentials recorded from pyramidal cells of the somatosensory cortex of wildtype (WT) (black) and 5xFAD (blue) mice. (b) Bar graphs displaying action potential (AP) threshold, AP amplitude and duration, input resistance, and afterhyperpolarization (AHP) of pyramidal cells from WT (black; n = 17) and 5xFAD mice (green; n = 24). (c) Example traces of action potential firing patterns recorded from somatosensory cortex pyramidal cells of WT (black) and 5xFAD (green) mice. (d) Bar graphs of firing frequency, early and late adaption of pyramidal cells from WT (black), and 5xFAD (green) mice. Data in bar graphs are shown as median ± interquartile range. Empty grey circles depict single data points.