Table 5b.

Comparison of baseline measurements of each biomarkers that changed with post-vaccination of placebo.

	Genes	day 0 and day 7Ψ			day 0 and day 28Ψ			day 0 and day 35Ψ			day 0 and day 42¥			day 0 and day 182¥
		Mean difference	SE Mean	p-value	Mean difference	SE Mean	p-value	Mean difference	SE Mean	p-value	Mean difference	SE Mean	p-value	Mean difference	SE Mean	p-value
Type-1 IFN inducible	IFI6	1660.33	562.55	0.098	1118.67	88.83	0.006	718.33	387.76	0.205	1650.67	870.80	0.198	1888.00	285.85	0.022
	IFIT5	53.33	242.18	0.846	381.33	64.06	0.027	107.00	69.35	0.263	104.67	115.51	0.461	483.67	235.96	0.177
	IFI44	464.33	601.68	0.521	896.66	255.9	0.073	187.67	44.82	0.050	113.06	115.47	0.432	770.00	341.56	0.153
	IFI44L	175.00	264.92	0.577	370.67	85.49	0.049	-22.00	156.04	0.901	189.33	109.41	0.226	250.33	255.65	0.431
	OAS3	-109.67	75.65	0.284	21.67	138.15	0.89	-211.33	43.23	0.039	59.33	152.09	0.734	-101.33	163.68	0.599
Innate immunity	NOD2	23.00	66.00	0.787	96.5	7.5	0.049	49.50	0.50	0.006	31.33	75.01	0.750	14.00	57.00	0.847

₳3 subjects; SE, Standard error; p-value obtained based on paired t-test. The significant p-values are in bold.