Table 4. Comet assay-measured variables in M. oleifera seed extract-treated and glutamate-treated retinal cells.
| COMET assay variables | Treatment | Concentration | |||
|---|---|---|---|---|---|
| 5 ug/ml | 10 ug/ml | 50 ug/ml | 100 ug/ml | ||
| Tail length (µm) | Control | 1.23 ± 0.09 | 1.23 ± 0.09 | 1.23 ± 0.09a | 1.23 ± 0.09 |
| Glutamate | 1.57 ± 0.13a | 2.03 ± 0.22a,# | 3.36 ± 0.32a,# | 4.62 ± 0.41a,# | |
| M. olifera | 1.11 ± 0.06 | 1.22 ± 0.06 | 1.26 ± 0.07# | 1.30 ± 0.08a | |
| Tail DNA (%) | Control | 1.24 ± 0.16 | 1.24 ± 0.16 | 1.24 ± 0.16 | 1.24 ± 0.16 |
| Glutamate | 1.83 ± 0.12a | 2.03 ± 0.11a,# | 3.06 ± 0.15a# | 3.85 ± 0.58a,# | |
| M. olifera | 1.22 ± 0.05 | 1.23 ± 0.03 | 1.26 ± 0.05 | 1.39 ± 0.03# | |
| Tail Moment (Unit) | Control | 1.51 ± 0.10 | 1.51 ± 0.10# | 1.51 ± 0.10# | 1.51 ± 0.10 |
| Glutamate | 2.88 ± 0.41a,# | 4.12 ± 0.44a,# | 10.32 ± 1.49a,# | 17.96 ± 4.09a,# | |
| M. olifera | 1.36 ± 0.11 | 1.49 ± 0.07# | 1.58 ± 0.08# | 1.82 ± 0.14# | |
Notes.
a
p < 0.001, value between each group and the control group.
#
p < 0.001 value between all groups.
All groups were compared using one-way ANOVA with Dunnett test (Multiple Comparisons) to compare each group with the control group Kruskal-Wallis test was used to compare all groups using parametric data. Mann–Whitney test was used to compare each group with the control group for non-parametric data.