Table 1.
Characteristics of Patients With and Without Community-Acquired Pneumonia per Gold Standard Manual Chart Review
| Characteristic | All Patients (n = 173) |
CAP (n = 71 [41%]) |
No CAP (n = 102 [59%]) |
P Value |
|---|---|---|---|---|
| Male sex | 96 (55.5) | 42 (59.2) | 54 (52.9) | .41 |
| Age, y, median (IQR) | 58 (46–67) | 58 (48–67) | 58 (41–67) | .38 |
| Fever (≥38°C) | 61 (35.3) | 32 (45.1) | 29 (28.4) | .02 |
| Hypothermia (≤36°C) | 84 (48.6) | 36 (50.7) | 48 (47.1) | .63 |
| Subjective fever or chills | 8 (4.6) | 4 (5.6) | 4 (3.9) | .59 |
| Tachypnea (≥24 breaths/min) | 95 (54.9) | 47 (66.2) | 48 (47.1) | .01 |
| Hypoxemia (SpO2 <92% or supplemental O2 received) | 121 (69.9) | 54 (76.1) | 67 (65.7) | .14 |
| WBC count >12 000 cells/mm3 | 84 (48.6) | 39 (54.9) | 45 (44.1) | .16 |
| WBC count <4000 cells/mm3 | 19 (11.0) | 9 (12.7) | 10 (9.8) | .55 |
| Abnormal pro-BNP (>125 pg/mL) | 66 (38.2) | 34 (47.9) | 32 (31.4) | .09 |
| Respiratory viruses | 33 (19.1) | 9 (12.7) | 24 (23.5) | .07 |
| Influenza viruses | 17 (9.8) | 7 (9.9) | 10 (9.8) | |
| Respiratory syncytial virus | 8 (4.6) | 1 (1.4) | 7 (6.9) | |
| Rhinoviruses/enteroviruses | 6 (3.5) | 1 (1.4) | 5 (4.9) | |
| Adenoviruses | 1 (0.6) | … | 1 (1.0) | |
| Metapneumovirus | 1 (0.6) | … | 1 (1.0) | |
| Blood culture for CAP pathogen | 4 (2.3) | 2 (2.8) | 2 (2.0) | |
| Staphylococcus aureus | 2 (1.2) | … | 2 (2.0) | |
| Streptococcus pneumoniae | 1 (0.6) | 1 (1.4) | … | |
| Haemophilus influenzae | 1 (0.6) | 1 (1.4) | … | |
| Bacterial urinary antigen | 4 (2.3) | 3 (4.2) | 1 (1.0) | .16 |
| Streptococcus pneumoniae | 4 (2.3) | 3 (4.2) | 1 (1.0) | |
| Sputum culture | 7 (4.0) | 7 (9.9) | … | |
| Staphylococcus aureus | 3 (1.7) | 3 (4.2) | … | |
| Haemophilus influenzae | 3 (1.7) | 3 (4.2) | … | |
| Moraxella catarrhalis | 1 (0.6) | 1 (1.4) | … | |
| Consolidation on either CXR or CTa | 69 (40) | 52 (73.3) | 17 (16.7) | <.01 |
| Consolidation on CXR | 30 (17) | 23 (32.4) | 7 (6.9) | <.01 |
| Consolidation on CT | 52 (30) | 41 (58) | 11 (11) | <.01 |
| Infiltrate on either CXR or CTa | 10 (5.8) | 6 (8.5) | 4 (3.9) | .20 |
Data are presented as No. (%) unless otherwise indicated. Bold P values indicate statistical significance.
Abbreviations: BNP, brain natriuretic peptide; CAP, community-acquired pneumonia; CXR, chest radiograph; CT, computed tomography; IQR, interquartile range; O2, oxygen; SpO2, oxygen saturation; WBC, white blood cell.
aPatients who had consolidation on both CXR and chest CT were counted only once.