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. 2021 Jun 22;43(1):968–979. doi: 10.1080/0886022X.2021.1936040

Figure 1.

Figure 1.

Serum from DN mice induced podocyte injury and endoplasmic reticulum stress. (A) MCP5 podocytes were treated either with 10% serum from control C57BL/KsJ dm/m mice or with 10% serum from C57BL/KsJ dm/dm DN mice for 24 h. Western blot image showing activation of PERK-eIF2α-ATF4 in ER stress signaling pathway and increased apoptosis-related molecule cleaved caspase-3 in podocytes treated with serum from DN mice as compared to control mice. (B) Densitometric quantification of protein expression from Figure 1(A). (**p < 0.01, *p < 0.05).