Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 11;8:656151. doi: 10.3389/fmolb.2021.656151

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Liu, Yu, Ge, Zhao, Miao, Jin, Su, Geng, Chen, Xie, Cui, Yao, Li, Hou and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

BAP31 promoted HCC progression via AKT/β-catenin/Snail pathway. (A,B) Western blot analysis showing protein expression of phosphorylated AKT, pan-AKT, β-catenin and BAP31 in HCC cells with overexpression and knockdown of BAP31. (C,D) Transwell assay analysis of the migratory and invasive abilities in Li-7 and Huh7 cells, which were divided into four groups: vector, BAP31 (DMSO-control), BAP31 (MK2206 2.5 μM) and BAP31 (MK2206 5 μM). (E) Fold change of Snail (SNAIL1) and E-cadherin (CDH1) mRNA expression in Li-7 and Huh7 cell, which were divided into four groups: vector, BAP31 (DMSO-control), BAP31 (MK2206 2.5 μM) and BAP31 (MK2206 5 μM). Results were presented as mean ± SD and t-test was conducted between vector and BAP31 (DMSO-control), BAP31 (DMSO-control) and BAP31 (MK2206 2.5 μM/5 μM) group (n = 3, *p < 0.05, **p < 0.01).