TABLE 2.

Proteins of An. neopropionicum and Ac. wieringae strain JM with significant changes (P value of <0.05 and a >1.3 log fold change) between days 4 and 15

Organism	Role	Protein	EC no.a	Pathway	Log fold change (day 4 vs. day 15)
An. neopropionicum	Vitamins	Riboflavin synthase	2.5.1.9	Vitamin B2 metabolism	3.2 ↑
		Putative thiamine biosynthesis protein	2.5.1.3	Vitamin B1 metabolism	2.1 ↑
		Aminopyrimidine aminohydrolase	3.5.99.2	Vitamin B1 metabolism	2.1 ↑
		Riboflavin biosynthesis protein RibBA/D	4.1.99.12	Vitamin B2 metabolism	2.4/2.8 ↑
	Amino acids	3-Isopropylmalate dehydratase small subunit	4.2.1.33	Isoleucine metabolism	2.1 ↓
		d-Serine dehydratase	4.3.1.18	Serine metabolism	3.3 ↑
		Aliphatic sulfonates import ATP-binding protein SsuB	7.6.2.14	Sulfated amino acid import	3 ↑
		Methionine import protein	7.4.2.11	Amino acid transport	1.3 ↑
		Glutamate synthase	1.4.1.13	Amino acid synthesis	3.5 ↑
		Aspartate semialdehyde dehydrogenase	1.2.1.11	Amino acid synthesis	3.3 ↑
		Asparagine tRNA ligase	6.1.1.22	Protein assembly	3.6 ↑
		Peptidyl-prolyl cis-trans isomerase	5.2.1.8	Proline isomerization	2.8 ↓
	Stress	Nitric oxide reductase	1.7.5.2	Redox stress	1.3 ↑
		Sporulation and spore germination	NA	Sporulation	2.6 ↑
Ac. wieringae strain JM	Vitamins	Pyridoxamine 5-phosphate oxidase	1.4.3.5	Vitamin B6	3.5 ↓
	DNA	DNA topoisomerase 1	5.6.2.1	DNA synthesis	3.3 ↓
		Anaerobic ribonucleoside-triphosphate reductase	1.17.4.2	DNA synthesis	3.1 ↓
		Dihydroorotate dehydrogenase	1.3.3.1	Pyrimidine metabolism	3.0 ↓
	Amino acids	Amino acid ABC transporter	NA	Amino acid transport	2.9 ↓
		Methionyl-tRNA formyltransferase	2.1.2.9	Protein assembly	2.9 ↓
		Methionine tRNA ligase	6.1.1.10	Protein assembly	3.3 ↑
		Glutamate tRNA ligase	6.1.1.17	Protein assembly	3.0 ↓
	Stress	MarR regulator	NA	Antibiotic resistance/oxidative stress	1.8 ↓

^aNA, not available in the database.