Appendix 1.

Allocation of Phases, suggested methods and the corresponding research items.

PHASE	SUGGESTED NAME OF PHASE/OBJECTIVE	SUITABLE METHODS OR INSTRUMENTS
0	State of the art research, including theoretical foundations for user acceptance [35,44]	Desk research
1	Analysing the user requirements [8,32,35,37,38,86,87,88,89,90,91] and the context of use [92,93]	Direct observations [32,89] Use cases [20,35,38] Expert panels of patients and health care providers [90] Workshops with patients [93] Semi-structured and field interviews with patients [35,37,38,88,89,90], their relatives, health care providers [32,35,37,38] and hospital managers [37] Quantitative surveys with patients [20,91] Focus groups with patients [32,38,87] and health care providers [87,88,93] Personas and user profiles of patients [20,32,35,86] and health care providers [35,86] Field studies [32,88]
2	Concept development [38] and deduction of characteristics of the prototype [37,86,87,88,89,91,92] based on an in-depth understanding of the user requirements [8,32,35,86,88,90,92,93] and context of use [8,90]	Use cases [38] Focus groups with patients [38] and health care providers [37] Semi-structured interviews with patients [38,88] and health care providers [38] Paper Prototyping or Sketching of the intended applications [20,35,88,90] Personas of patients [90] Prototyping [32,35,86,87,88,89]
3	Development [8,32,35,38,86,87,89,90,92,93] and adaption [32,86,87] of the prototype based on a first evaluation [8,20,35,37,86,87,88,89,91,92] of its usability in controlled environments	Cognitive walkthrough with health care providers [20] Heuristic evaluation with non-users [20,93] Think aloud studies with health care providers [20,88,92], patients [88,92,93] and their relatives [89] Interview [87,89,90] Quantitative surveys with patients [20,37,88,90,91,93] and health care providers [20,87,88], using usability questionnaires
4	Evaluating [8,32,37,38,86,89,93] and adapting [37,91,93] the application in terms of usability and user acceptance under real-life conditions	Field studies [88] Focus groups with health care providers [37] Quantitative surveys with patients [20,37,88,90,91,93] and health care providers [20,88], using usability questionnaires
5	Implementation [32,35,37,91,92] of the full-scale application and long-term evaluation [35,37,90,93]	Semi-structured interview with patients [38,92] and health care providers [92]