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Schematic diagram of TUG1 involved in CIRI regulation. TUG1 was highly expressed in the serum of CIRI patients. TUG1 inhibited the proliferation, promoted inflammation, oxidative stress and apoptosis, cytotoxicity and activated JNK and p38 pathways by sponging miR-493-3p or miR-410-3p in CIRI progression.
