Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 23;16(1):630–640. doi: 10.1515/biol-2021-0062

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Md. Mehedi Hassan et al., published by De Gruyter

This work is licensed under the Creative Commons Attribution 4.0 International License.

PMC Copyright notice

Comparison of SARS-CoV-2 and Bat-CoVs. (a) The phylogeny of SARS-CoV-2 based on the 14 ORF and receptor-binding domain (RBD) sequences of Bat-CoV, Pan-CoV, Bat-SL-CoV, and SARS-CoV. Phylogenies were estimated by the neighbor-joining method using Unipro UGENE bioinformatics toolkits. (b) Organization of genes in SARS-CoV-2 and Bat-CoVs. The distribution of mutated amino acids in SARS-CoV-2 compare to Bat-CoV are represented with red lines. (c) Homotrimer 3D model of Bat-CoV and SARS-CoV-2 spike protein constructed using the SWISS-MODEL protein homology-modeling server. Circle showing the altered surface structure in the spike region of SARS-CoV-2 for antigen binding.