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. 2021 Jun 12;10(6):1484. doi: 10.3390/cells10061484

Figure 6.

Figure 6

XN interferes with PMA-dependent activation of AKT, FAK, and ERK1/2, kinases in A549 cells. The cells were pre-treated with XN for 4 h and then co-treated with PMA for 24 h; the amounts of phosphorylated ERK1/2, FAK, and AKT were determined with the ELISA assay. Quantitative analysis of (a) p-AKT/tAKT, (b) p-FAK/tFAK, and (c) p-ERK/tERK ratio. Data are expressed as means ± SD of three independent experiments. *** p < 0.001 compared to the PMA-only treatment, # p < 0.05 or ### p < 0.001 compared to the non-stimulated cells; one-way ANOVA test.