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. 2021 Jun 12;13(12):2958. doi: 10.3390/cancers13122958

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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GEP analysis and GSEA results of the genes related to SELPLG. GEP analysis identified the presence of several genes showing a positive Pearson product-moment correlation coefficient (0.75–1) with SELPLG gene expression in ALCLs (A), non-ALCL PTCLs (B) and non-neoplastic samples (C). SELPLG gene presented 1358 significantly correlated genes in the ALCL setting (red), 242 in non-neoplastic samples (cyan) and 1 in non-ALCL PTCLs (green). In total, 1324 were exclusively correlated with the SELPLG gene within the ALCL setting (D). GSEA results of the genes related to SELPLG in ALCLs, comprising hallmark gene sets (E), C2 curated gene sets, chemical and genetic perturbations (F) and GO enrichment analysis (G).