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Cell-mediated immunity (IFN-γ and granzyme B levels) to the four vaccine antigens: (a) A(H1N1); (b) A(H3N2); (c) B(Yamagata lineage); (d) B(Victoria lineage). IFN-γ and granzyme B levels were measured at pre-vaccination (0), two weeks post-vaccination (2 wks), and five months post-vaccination (5 mos).
