Table 3.
n-fold gene expression in PE-CA/PJ49 or FaDu tumor cells versus normal HaCaT cells treated for 24 h with 10 μM CisPt and/or 50 μM RSV. The results were obtained using gene reference HPRT. Control is represented by the untreated cells of each cell line, and the n-fold expression for each gene analyzed in control cells was 1.
n-Fold Gene Expression/Treatment | HaCaT | PE/CA-PJ49 | FaDu | ||||||
---|---|---|---|---|---|---|---|---|---|
CisPt | RSV | CisPt + RSV |
CisPt | RSV | CisPt + RSV |
CisPt | RSV | CisPt + RSV |
|
TP53 | 0.69 | 0.82 | 3.05 | 1.18 | 1.44 | 0.59 | 2.7 | 2.5 | 2.4 |
MDM2 | 1.7 | 5.3 | 7.3 | 1.2 | 7.9 | 4.2 | 0.65 | 0.46 | 0.37 |
BCL2 | 0.98 | 0.27 | 0.62 | 0.29 | 0.96 | 0.59 | 0.46 | 0.33 | 0.17 |
c-MYC | 0.84 | 0.47 | 0.74 | 0.75 | 1.11 | 0.44 | 0.45 | 0.22 | 2.3 |