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. 2021 Jun 12;13(6):2030. doi: 10.3390/nu13062030

Figure 2.

Figure 2

Oral HA 35 KDa supplementation from P7–P14 increases villi length (A) and crypt depth (B) in mouse pups (n = 206 villi/crypts; p = 0.0085 (illi length) p < 0.0001 (crypt depth). A comparison of Ki67 staining (brown) of the ileum in controls (C) and HA 35 KDa (D) pups indicates increased intestinal epithelial proliferation with oral HA 35 KDa. Quantification (n = 131 crypts; p = 0.0175) of Ki67 staining in (E). Data presented as mean ± SEM. HA: hyaluronic acid; * p < 0.05; ** p < 0.01; **** p < 0.0001.