A diagonal classifier agreement plot between the image maximum intensity
projection (MIP) and feature MIP methods. The x-axis and y-axis denote
the probability of malignancy (PM) scores predicted by the image MIP
classifier and feature MIP classifier, respectively. Each point
represents a lesion for which predictions were made. Points along or
near the diagonal from bottom left to top right indicate high classifier
agreement; points far from the diagonal indicate low agreement. The
insets are the MIP regions of interest (ROIs) and three-dimensional (3D)
ROIs, which served as convolutional neural network inputs for the image
MIP and feature MIP methods, respectively, of extreme examples for which
using feature MIP resulted in more accurate predictions than using image
MIP (lesions 1–2), for which using image MIP resulted in more
accurate predictions than using feature MIP (lesion 3), and for which
the two methods both predict accurately (lesions 4–5). Lesion 1
is an invasive micropapillary carcinoma, lesion 2 is fibromatosis,
lesion 3 is a grade II invasive ductal carcinoma, lesion 4 is a grade II
invasive ductal carcinoma, and lesion 5 is a nonmass enhancement
fibroadenoma. RGB = red, green, and blue.