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. 2021 Jun 13;26(12):3625. doi: 10.3390/molecules26123625

Table 5.

Minimal inhibition concentration (MIC), minimal bactericidal concentration (MBC), and MBC/MIC ratio showing quantitative antibacterial activity of two EOs (C. carvi and C. sativum) and their mixture against human pathogenic bacteria compared to standard antibiotics (gentamycin and tetracycline).

Microorganisms Tested C. carvi EO C. sativum EO Mixture (v/v) EOs Antibiotics
MIC
mg/mL
MBC
mg/mL
MBC/MIC
(Interpretation)
MIC
mg/mL
MBC
mg/mL
MBC/MIC
(Interpretation)
MIC
mg/mL
MBC
mg/mL
MBC/MIC
(Interpretation)
MIC
mg/mL
MBC
mg/mL
MBC/MIC
S. epidermidis CIP 106510 0.117 0.469 4 (Bactericidal) 0.469 1.875 4 (Bactericidal) 0.029 0.117 4 (Bactericidal) 0.009 0.039 4
S. aureus ATCC 25923 0.117 0.469 4 (Bactericidal) 0.234 0.938 4 (Bactericidal) 0.059 0.234 4 (Bactericidal) 0.004 0.019 4
M. luteus NCIMB 8166 0.059 0.234 4 (Bactericidal) 0.234 0.938 4 (Bactericidal) 0.015 0.059 4 (Bactericidal) 0.004 0.019 4
E. feacalis ATCC 29212 0.059 0.469 8 (Bacteriostatic) 0.469 0.938 2 (Bactericidal) 0.117 0.234 2 (Bactericidal) 0.004 0.019 4
B. cereus ATCC 11778 0.117 0.469 4 (Bactericidal) 0.938 1.875 2 (Bactericidal) 0.059 0.117 2 (Bactericidal) 0.004 0.039 8
B. cereus ATCC 14579 0.117 0.469 4 (Bactericidal) 0.938 1.875 2 (Bactericidal) 0.059 0.234 4 (Bactericidal) 0.004 0.039 4
E. coli ATCC 35218 0.469 1.875 4 (Bactericidal) 0.938 3.750 4 (Bactericidal) 0.117 0.469 4 (Bactericidal) 0.009 0.039 4
L. monocytogenes ATCC19115 0.469 1.875 4 (Bactericidal) 0.938 1.875 2 (Bactericidal) 0.059 0.234 4 (Bactericidal) 0.019 0.078 4
P. aeruginosa ATCC 27853 1.875 3.750 2 (Bactericidal) 1.875 7.500 4 (Bactericidal) 0.469 0.938 2 (Bactericidal) 0.019 0.15 4
S. typhimurium LT2 DT104 0.234 0.938 4 (Bactericidal) 0.938 1.875 2 (Bactericidal) 0.059 0.117 2 (Bactericidal) 0.019 0.039 2
V. parahaemolyticus ATCC17802 0.938 3.750 4 (Bactericidal) 0.234 1.875 8 (Bacteriostatic) 0.117 0.234 2 (Bactericidal) 0.039 0.078 2
V. alginolyticus ATCC 33787 0.234 1.875 8 (Bacteriostatic) 1.875 7.500 4 (Bactericidal) 0.059 0.469 8 (Bacteriostatic) 0.019 0.078 4
V. proteolyticus ATCC15338 0.469 1.875 4 (Bactericidal) 1.875 3.750 2 (Bactericidal) 0.117 0.469 4 (Bactericidal) 0.009 0.039 4
V. furnisii ATCC 35016 0.469 3.750 8 (Bacteriostatic) 1.875 7.500 4 (Bactericidal) 0.117 0.469 4 (Bactericidal) 0.009 0.039 4
V. mimicus ATCC 33653 0.938 3.750 4 (Bactericidal) 1.875 7.500 4 (Bactericidal) 0.234 0.938 4 (Bactericidal) 0.039 0.078 2
V. natrigens ATCC 14048 1.875 3.750 2 (Bactericidal) 1.875 3.750 2 (Bactericidal) 0.469 0.938 2 (Bactericidal) 0.019 0.039 2
V. carhiaccae ATCC 35084 0.938 1.875 2 (Bactericidal) 1.875 7.500 4 (Bactericidal) 0.117 0.234 2 (Bactericidal) 0.039 0.078 2
V. fluvialis ATCC 33809 0.469 1.875 4 (Bactericidal) 0.469 3.75 8 (Bacteriostatic) 0.117 0.469 4 (Bactericidal) 0.019 0.039 2