Table 2.
Ratio of the mean EV count between survivors and not-survivors subjects. p-value is estimated by linear Poisson regression models, allowing for overdispersion.
| Amniotic Fluid | Tracheal Fluid | |||
|---|---|---|---|---|
| Ratio Non-Survivor/Survivor | p-Value * | Ratio Non-Survivor/Survivor | p-Value * | |
| A—Nanoparticle Tracking Analysis | ||||
| Total EV | 1.28 | <0.0001 | 3.12 | <0.0001 |
| Exosomes (<130 nm) | 1.06 | 0.0965 | 1.94 | <0.0001 |
| Microvesicles (>130 nm) | 1.29 | <0.0001 | 3.17 | <0.0001 |
| B—Flow Cytometry | ||||
| CD66+ (neutrophils) | 1.41 | <0.0001 | 0.97 | 0.6873 |
| CD14+ (monocytes/macrophages) | 1.42 | <0.0001 | 1.33 | 0.0005 |
| CD105+ (endothelium) | n/a | n/a | 1.5 | <0.0001 |
| EpCAM+ (epithelium) | 1.55 | <0.0001 | 1.32 | 0.0010 |
| HLAG+ (placenta) | 1.43 | <0.0001 | n/a | n/a |
| HERV-W+ (placenta) | 1.13 | 0.0008 | n/a | n/a |
* p-value of the model comparing mean count in survivors versus mean count in non-survivors. Means and confidence intervals are reported in Supplementary Table S2.