Table 3.
Mean concentrations of EV-miRNA levels in survivors and non-survivors measured by OpenArray (miRNA selected for validation only).
| Amniotic Fluids | Tracheal Fluids | |||
|---|---|---|---|---|
| miRNA | Fold Change | p-Value * | Fold Change | p-Value * |
| mir-200a-5p | 0.450 | 0.2569 | 2.087 | 0.0005 |
| mir-17-3p | Not expressed | Not expressed | 0.268 | 0.0084 |
| mir-200b-5p | 0.247 | 0.2630 | 0.004 | 0.0104 |
| mir-548d-5p | 1.926 | 0.1540 | 3.381 | 0.0148 |
| mir-503-5p | 1.883 | 0.1116 | 2.129 | 0.0154 |
| mir-505-5p | 1.287 | 0.9787 | 0.191 | 0.0169 |
| mir-223-3p | 1.314 | 0.3905 | 3.506 | 0.0226 |
| mir-29b-3p | 1.261 | 0.5726 | 2.685 | 0.0241 |
| mir-379-5p | 2.425 | 0.0378 | 0.614 | 0.3493 |
| mir-190-5p | 2.546 | 0.0478 | 1.728 | 0.1021 |
| mir-889-3p | 2.094 | 0.0571 | 0.659 | 0.5155 |
* p-value of the model comparing mean count in not-survivors versus mean count in survivors. Complete miRNA expression levels of the screening are reported in Supplementary Table S3.