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. 2021 Jun 14;7(6):481. doi: 10.3390/jof7060481

Table 3.

Summary of the signs and symptoms of histoplasmosis in people living with HIV or other immunocompromising conditions, and the organs in which Histoplasma spp. was demonstrated.

People Living with HIV Other Immunocompromising Conditions
Signs and Symptoms,
No. (%)
Organs in which
Histoplasma was
Demonstrated, No.
Signs and Symptoms,
No. (%)
Organs in which
Histoplasma was
Demonstrated, No.
Fever, 57/78 (73.1)
Splenomegaly, 22/32 (65.6)
Hepatomegaly, 21/32 (65.6)
Lymph node
enlargement, 40/78 (51.3)
Weight loss, 38/78 (48.7)
Skin lesions, 25/78 (32.0)
Cough, 20/78 (25.6)
Dyspnoea, 17/78 (21.8)
Diarrhoea, 14/78 (17.9)
Abdominal pain, 10/78 (12.8)
Nausea, 5/78 (6.4)
Bone marrow, 38
Blood, 29
Lymph nodes, 29
Lung, 24
Skin, 20
Intestine, 12
Liver, 8
Peripheral blood smear, 5
Oropharyngeal mucosa, 5
Cerebrospinal fluid, 2
Larynges, 2
Tonsils, 2
Pleural fluid, 1
Vagina, 1
Brain biopsy, 1
Oesophagus, 1
Fever, 17/26 (65.4)
Weight loss, 11/26 (42.3)
Cough, 9/26 (34.6)
Dyspnoea, 7/26 (26.9)
Diarrhoea, 6/26 (23.1)
Skin lesions, 5/26 (19.2)
Hepatomegaly, 4/26 (15.4)Lymph node
enlargement, 4/26 (15.4)
Abdominal
pain, 3/26 (11.5)
Splenomegaly, 1/26 (3.8)
Nausea, 0/26 (0)
Lung, 8
Bone marrow, 6
Oropharyngeal mucosa, 6
Lymph nodes, 6
Skin, 5
Intestine, 4
Liver, 3
Kidney, 2
Brain biopsy, 1
Muscle, 1
Spleen, 1
Synovial membrane, 1
Blood, 1
Mitral valve, 1