Table 2.
Analysis of in-breast tumor recurrences after a five-year follow-up period between partial-breast irradiation and whole-breast irradiation for the whole group and by technique. The prevalence rates by treatment arm and the statistical comparison using the odds ratios with the corresponding 95% confidence intervals are given. The bold p-values are considered statistically significant.
| Five-Year in-Breast Tumor Recurrence | |||||||
|---|---|---|---|---|---|---|---|
| Study | Rate [%] PBI | Rate [%] WBI | OR | LCI 95% | HCI 95% | Weight (%) | p-Value |
| NSABP B-39 | 2.68 | 2.26 | 1.19 | 0.80 | 1.77 | 42.5 | |
| Budapest | 3.91 | 3.08 | 1.28 | 0.34 | 4.88 | 3.7 | |
| IBTR 5y EBTR/BT | 2.76 | 2.32 | 1.20 | 0.82 | 1.75 | 46.2 | 0.349 |
| RAPID | 2.35 | 1.67 | 1.42 | 0.75 | 2.70 | 15.9 | |
| IMPORT LOW | 0.53 | 1.04 | 0.51 | 0.13 | 1.97 | 3.6 | |
| Florence | 2.31 | 1.15 | 2.02 | 0.50 | 8.18 | 3.4 | |
| IBTR 5y EBTR | 1.70 | 1.41 | 1.17 | 0.44 | 3.15 | 22.9 | 0.749 |
| ELIOT | 4.26 | 0.52 | 8.53 | 2.56 | 28.50 | 4.6 | |
| TARGIT prepath | 2.11 | 0.95 | 2.24 | 1.09 | 4.60 | 12.8 | |
| TARGIT postpath | 3.96 | 1.05 | 3.89 | 1.57 | 9.62 | 8.1 | |
| IBTR 5y IORT | 3.07 | 0.90 | 3.39 | 1.64 | 7.00 | 25.4 | 0.001 |
| GEC ESTRO | 1.57 | 1.02 | 1.55 | 0.52 | 4.65 | 5.5 | |
| IBTR 5y BT | 1.57 | 1.02 | 1.55 | 0.52 | 4.65 | 5.5 | 0.436 |
| Total 5y IBTR | 2.47 | 1.46 | 1.61 | 0.97 | 2.66 | 100.0 | 0.066 |
| I2 | 53.45 | 1.14 | 78.08 | ||||
| Cochran’s Q | 17.19 | ||||||
| Chi2, p | 0.028 | ||||||