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Loss of nuclear BAP1 expression in a BAP1-inactivated melanocytoma. This tumor displays nuclear pleomorphism. A, Hemotoxylin and eosin (H&E), ×100. B, H&E, ×400. C, BAP1 immunohistochemistry, ×400. Large epithelioid tumor cells have lost BAP1 expression (arrow). Lymphocytes show normal nuclear expression of BAP1 (arrowhead)
