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. 2021 Jun 15;10(6):1214. doi: 10.3390/plants10061214

Table 3.

Antifungal potent of Cistus extracts.

Cistus Species Collection Area Part of Plant Type of Extract Fungi MIC µg/mL MGI % References
C. creticus Greece Leaves EO C. albicans MID (1/250) ND [69]
C. criticus
subsp. eriocephalus
Kandanos
Chania, Greece
Aerial parts EO C. albicans MID (<1/200) ND [70]
C. criticus
subsp. creticus
MID (<1/250)
C. ladaniferus ND ND Essential Oil;
Concrete; Absolute
and Resinoid
A. niger
B. cinerea
M. racemosus
V. albo-atrum
4000 to 10,000 ppm
of EO
99.4%
(M. racemosus)
[139]
C. villosus Ourika,
Morocco
Leaves Methanolic extracts
and their fractions
A. fumigatus
C. albicans
C. krusei
C. glabrata
100,000 to 200,000
1560 to 200,000
6250 to >200,000
190 to 390
ND [131]
C. monspeliensis A. fumigatus
C. albicans
C. krusei
C. glabrata
25,000 to 200,000
25,000 to 200,000
12,500 to 100,000
1560 to 3125
C. villosus Agadir,
Morocco
Leaves+stem Plant powders P. digitatum
P. italicum
G. candidum
ND 100%
100%
100%
[135]
EO 37%
30%
18%
Methanolic 77%
17%
79%
Chloroformic 27%
27%
21%
C. villosus Agadir,
Morocco
Leaves and stem Aqueous G. candidum 156 100% [136]
C. ladanifer Montesinho,
Portugal
Leaves Phenolic extract C. albicans
C. tropicalis
C. glabrata
C. parapsilosis
<50
625
<50
<50
ND [132]
C. incanus Greece ND Hydro-methanolic A. parasiticus
A. carbonarius
ND 45.91%
30.65%
[133]
C. incanus Turkey Unknown Aqueous C. albicans
C. glabrata
32,000
8000
ND [31]
C. albidus Morocco Aerial parts Aqueous Geotrichumcitri-aurantii >10,000 >80% [137]
C. creticus Aerial parts 1250 100%
C. laurifolius Aerial parts <625 100%
C. salviifolius Aerial parts <625 ND
C. monspeliensis Aerial parts <625 100%
C. ladanifer Aerial parts <625 100%
C. crispus Aerial parts >10,000 100%
C. populifolius Leaves <625 100%
C. creticus Tafraout,
Morocco
Leaves EO C. versicolor
G. trabeum
C. puteana
P. placenta
P. digitatum
P. expansum
A. niger
1/64
1/250
1/1000
1/2000
1/100
1/32
1/100
ND [134]
Ethanolic >10,000
1000
>10,000
1000
1000
>10,000
>10,000
C. salviifolius
C. monspeliensis
Jendouba,
Tunisia
Leaves Ethanol
Hexane
Water
C. albicans
A. niger
ND 6300–12,500
3100–12,500
[141]

ND: Not determined; C. albicans: Candida albicans; A. niger: Aspergillus niger; B. cinerea: Botrytis cinerea; M. racemosus: Mucor racemosus: Verticilliumalbo-atrum; A. fumigatus: Aspergillus fumigatus; C. krusei: Candida krusei; C. glabrata: Candida glabrata; P. digitatum: Penicillium digitatum; P. italicum: Penicillium italicum; G. candidum: Geotrichum candidum; C. tropicalis: Candida tropicalis; C. parapsilosis: Candida parapsilosis; A. parasiticus: Aspergillus parasiticus; A. carbonarius: Aspergillus carbonarius; C. versicolor: Coriolus versicolor; G. trabeum: Gloeophyllum trabeum; C. puteana: Coniophora puteana; P. placenta: Poria placenta; P. digitatum: Penicillium digitatum; P. expansum: Penicillium expansum.