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. 2021 Jun 11;11:681946. doi: 10.3389/fonc.2021.681946

Table 3.

Univariate and multivariate analyses of the prognostic model.

Clinical characteristics Univariate Cox Multivariate Cox
HR 95%CI P HR 95%CI P
Training group (N=102)
Age (years, mean ± SD) 1.039 0.513-1.994 7.88E-01 1.004 0.964-1.045 8.62E-01
Pathological stage (I/II/III/IV/-) 4.465 2.197-9.824 4.57E-05 3.348 1.649-7.355 1.07E-03
Radiotherapy (Yes/No/-) 0.877 0.246-3.126 8.40E-01 0.833 0.507-2.730 3.77E-01
PS model status (High/Low) 10.06 2.164-16.75 2.64E-04 2.512 1.552-9.978 1.75E-02
Validation group (N=298)
Age (years, mean ± SD) 1.024 1.012-1.036 9.94E-05 1.022 1.007-1.037 3.31E-03
Pathological stage (I/II/III/IV/-) 1.625 1.201-2.197 1.57E-03 1.687 1.249-2.278 6.46E-04
Radiotherapy (Yes/No/-) 0.841 0.601-1.177 3.13E-01 0.853 0.564-1.290 4.51E-01
PS model status (High/Low) 1.437 1.050-1.966 2.27E-02 1.541 1.071-2.219 1.98E-02

CI, confidence interval; HR, hazard ratio. The bold values represent statistically significant (P < 0.05).