Figure 6.

ETL downregulates human IL1A expression by preventing the MEK/ERK and PI3K/AKT signaling pathway in MDA231 TNBC cells. (A,B) after cell-seeding, 5μM of inhibitor was treated to the cells for 24 h. The levels of IL1A mRNA (A) and protein (B) were measured through real-time PCR and ELISA, respectively. (C) the levels of p- and t-ERK and AKT were measured through Western blotting. The values are presented as the mean ± standard error of three independent experiments. ** p < 0.01 vs. Con. Con; control, ETL; Entelon^®.