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. 2021 Jun 15;26(12):3644. doi: 10.3390/molecules26123644

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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ETL prevents the tumor growth and metastatic capacity of TNBC cells. (A) schematic model of the experimental procedure. (B) the size of the tumors in each group (n = 5) was measured and analyzed for 15 days. (C) the results, confirmed by immunohistochemistry, were scored. Quantitative data were obtained through the calculation of four fields to analyze the experimental results of Ki-67 and TUNEL-positive cells. (D) after 15 days, the lung tissues were dissected and analyzed for metastatic events. The number of metastatic nodules was counted in the lung tissue. The values are presented as the mean ± standard error of independent experiments. * p < 0.05, ** p < 0.01 vs. (−) control. Scale bar = 100 μm.