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. 2021 Jan 28;5:PO.20.00171. doi: 10.1200/PO.20.00171

FIG 2.

FIG 2.

(A) A 3-year-old patient underwent ultrasound-guided biopsy of a left inguinal lymph node using a 16G Biopince biopsy instrument, yielding an next-generation sequencing (NGS)–adequate neuroblastoma sample. (B) A 6-year-old patient underwent fluoroscopically guided biopsy of a radiologically evident right 8th rib lesion using a 15G Bonopty biopsy instrument, yielding an NGS-adequate neuroblastoma sample. (C) A 9-year-old patient underwent conventional computed tomography (CT)–guided biopsy of a radiologically evident right iliac lesion using a 15G Bonopty instrument, yielding an NGS-adequate neuroblastoma sample. (D) An 8-year-old patient underwent biopsy of a radiologically evident left sacral lesion with guidance from C-arm CT with iGuide software using a 13G OnControl biopsy instrument, yielding an NGS-adequate neuroblastoma sample. (E) An 8-year-old patient underwent biopsy of a radiologically occult left tibial lesion with guidance from fluoroscopy with 2D magnetic resonance (MR) overlay using a 13G OnControl biopsy instrument, yielding an NGS-adequate neuroblastoma sample (lesion outlined in pink). (F) A 13-year-old patient underwent biopsy of a radiologically occult left iliac lesion with guidance from C-arm CT with 3D MR overlay using a 15G Bonopty biopsy instrument, yielding a sample that was neuroblastoma-positive but inadequate for NGS.