. 2021 Jun 15;10(6):1379. doi: 10.3390/foods10061379

Table 5.

Hydrolyzates and fractions with molecular mass <3.0 kDa as inhibitors of enzymes involved in metabolic syndrome (EC₅₀ mg mL⁻¹).

	ACE	Lipase	LOX	α-Amylase
Samples	ACE	Lipase	LOX	α-Amylase
Hydrolyzates
Control	1.52 ± 0.29 ^aA	0.57 ± 0.02 ^aA	2.33 ± 0.22 ^bC	3.77 ± 0.06 ^aC
0.5 SJW	1.26 ± 0.09 ^aA	1.48 ± 0.05 ^bB	2.47 ± 0.56 ^bC	1.72 ± 0.06 ^bB
1.0 SJW	1.24 ± 0.03 ^aA	1.90 ± 0.15 ^cB	1.03 ± 0.02 ^aB	0.05 ± 0.008 ^cA
Fractions with molecular mass <3.0 kDa
Control	0.46 ± 0.03 ^aB	0.12 ± 0.005 ^aA	0.44 ± 0.4 ^aAB	0.029 ± 0.006 ^bA
0.5 SJW	0.33 ± 0.04 ^bB	0.17 ± 0.005 ^abA	0.24 ± 0.001 ^bA	0.019 ± 0.006 ^abA
1.0 SJW	0.58 ± 0.05 ^cB	0.19 ± 0.04 ^bA	0.076 ± 0.001 ^cA	0.013 ± 0.003 ^aA

Control—cookies without St. John’s wort; 0.5 SJW—cookies enriched with 0.5% of St. John’s wort; 1.0 SJW—cookies enriched with 1% of St. John’s wort. All values are mean ± standard deviation for triplicate experiments. Different capital letters in the same column indicate significant differences for the same indicator (α = 0.05). Different lowercase letters in the same type of samples indicate significant differences for the same indicator (α = 0.05).