Table 3. Physiological variables in preterm lambs over the first 6 days of life.
| Variable | Day | Experimental group | ||
|---|---|---|---|---|
| Sal/Sal | LPS/Sal | LPS/hAECs | ||
| Proportion time on mechanical ventilation (%) | 1 | 19.9 | 44.0 | 75.7 |
| 2 | 11.1 | 57.4 | 89.9 | |
| 3 | 10.2 | 51.8 | 79.9 | |
| 4 | 26.9 | 36.6 | 75.0 | |
| 5 | 29.2 | 33.8 | 94.4 | |
| 6 | 0.0 | 41.7 | 83.3 | |
| FiO2 | 1 | 0.23 ± 0.0 | 0.22 ± 0.0 | 0.22 ± 0.0 |
| 2 | 0.21 ± 0.0 | 0.23 ± 0.0 | 0.22 ± 0.0 | |
| 3 | 0.23 ± 0.0 | 0.23 ± 0.0 | 0.23 ± 0.0 | |
| 4 | 0.23 ± 0.0 | 0.27 ± 0.1 | 0.23 ± 0.0 | |
| 5 | 0.24 ± 0.0 | 0.30 ± 0.2 | 0.24 ± 0.0 | |
| 6 | 0.24 ± 0.0 | 0.26 ± 0.1 | 0.27 ± 0.0 | |
| Mean BP (mmHg) | 1 | 61 ± 2 | 62 ± 1 | 60 ± 3 |
| 2 | 50 ± 2 | 58 ± 2 | 59 ± 1 | |
| 3 | 63 ± 3 | 60 ± 2 | 62 ± 1 | |
| 4 | 62 ± 2 | 63 ± 2 | 62 ± 2 | |
| 5 | 64 ± 2 | 63 ± 2 | 62 ± 4 | |
| 6 | 62 ± 2 | 68 ± 3 | 62 ± 3 | |
| HR (beats/min) | 1 | 221 ± 17 | 212 ± 22.09 | 195 ± 17 |
| 2 | 200 ± 16 | 191 ± 26.94 | 195 ± 31 | |
| 3 | 201 ± 28 | 190 ± 26.44 | 186 ± 31 | |
| 4 | 215 ± 30 | 186 ± 26* | 197 ± 28 | |
| 5 | 213 ± 24 | 193 ± 32 | 202 ± 23 | |
| 6 | 222 ± 22 | 208 ± 29 | 211 ± 17 | |
| RR (breaths/min) | 1 | 54 ± 2 | 55 ± 2 | 51 ± 2 |
| 2 | 58 ± 2 | 49 ± 3 | 50 ± 4 | |
| 3 | 54 ± 3 | 50 ± 2 | 47 ± 4 | |
| 4 | 54 ± 3 | 53 ± 2 | 49 ± 3 | |
| 5 | 52 ± 4 | 56 ± 3 | 53 ± 4 | |
| 6 | 61 ± 4 | 55 ± 4 | 49 ± 3* | |
Data are mean ± SD.
*P<0.05 compared to Sal/Sal. FiO2: fraction of inspired oxygen; BP: blood pressure; HR: heart rate; RR: respiratory rate. Data analysed using 2 way repeated measures ANOVA, with time as a factor.