Table 7. Analysis of sensitivity/specificity of RDTs and PCR assay results stratified by age, gender and diarrheal disease severity (PCR as the gold standard).
Assay kit | Age | Gender | Disease severity | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Less than 5 years | More than 5 years | Male | Female | Severe | Moderate/mild | |||||||
Se | Sp | Se | Sp | Se | Sp | Se | Sp | Se | Sp | Se | Sp | |
SD Cholera | 26.9 | 97.7 | 55.6 | 95.9 | 53.4 | 93.7 | 51.3 | 98.6 | 52.9 | 95.6 | 52.1 | 96.3 |
SMART—II | 38.5 | 93.0 | 60.8 | 92.2 | 60.2 | 88.2 | 56.4 | 96.5 | 52.9 | 91.1 | 59.1 | 92.5 |
Crystal VC | 30.8 | 95.3 | 58.8 | 97.1 | 56.3 | 95.1 | 54.7 | 98.6 | 52.9 | 97.8 | 55.9 | 96.7 |
Sensitivity (Se) and specificity (Sp) values are in percentage. PCR assay as gold standard