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. 2021 Jun 25;16(6):e0253537. doi: 10.1371/journal.pone.0253537

Table 1. Characteristics of the study population according to glycaemic status by glycated haemoglobin A1c (HbA1c) or Fasting Plasma Glucose (FPG).

Variable Normoglycaemia Pre-diabetes Type 2 diabetes
HbA1c ADA HbA1c WHO-IEC FPG ADA HbA1c ADA HbA1c WHO-IEC FPG ADA HbA1c FPG
n = 651 n = 1043 n = 1038 n = 586 n = 194 n = 211 n = 99 n = 90
Male (%) 336 (51.6) 509 (48.8) 480 (46.2) 269 (45.9) 96 (49.5) 133 (63.0) 67 (67.7) 61 (67.8)
Age, years (median) 64.2 (59.8─68.4) 64.5 (60.2─68.8) 64.5 (60.2─68.9) 65.7 (61.2─70.1) 67.0 (62.3─71.2) 66.3 (61.5─70.7) 66.4 (63.4─69.7) 66.9 (64.1─70.0)
Age, ≥65 years (%) 294 (47.8) 488 (49.7) 486 (50.1) 306 (55.8) 112 (61.5) 122 (60.4) 62 (70.5) 58 (72.5)
Married or cohabiting (%) 517 (79.9) 826 (79.6) 824 (79.7) 447 (76.4) 138 (71.1) 151 (71.9) 78 (78.8) 69 (76.7)
Health rating, very good or good (%) 581 (89.7) 910 (87.5) 910 (87.9) 492 (84.0) 163 (84.0) 168 (79.6) 69 (69.7) 63 (70.0)
Primary education only (%) 130 (21.6) 222 (22.9) 208 (21.7) 140 (25.7) 48 (27.0) 62 (30.8) 32 (36.0) 31 (38.8)
Current smoker (%) 43 (6.6) 89 (8.6) 89 (8.6) 62 (10.6) 16 (8.2) 19 (9.0) 10 (10.1) 9 (10.0)
High alcohol intake (%) 55 (11.2) 79 (10.2) 68 (9.2) 39 (9.8) 15 (13.3) 23 (14.9) 2 (3.3) 4 (7.3)
Low-level physical activity (%) 448 (69.1) 744 (71.5) 738 (71.3) 428 (73.0) 132 (68.0) 149 (70.6) 70 (70.7) 64 (71.1)
DASH score (mean) 24.6 ± 5.6 24.5 ± 5.5 24.6 ± 5.5 24.1 ± 5.4 23.7 ± 5.3 23.4 ± 5.5 23.5 ± 5.4 23.3 ± 5.4
Poor diet qualitya (%) 255 (39.6) 422 (41.0) 412 (40.2) 260 (44.9) 93 (48.2) 109 (52.4) 49 (52.1) 46 (54.8)
BMI, kg/m2 (mean) 27.7 ± 4.6 28.1 ± 6.3 27.7 ± 4.6 29.0 ± 7.4 29.5 ± 4.8 31.0 ± 10.2 31.0 ± 4.6 31.3 ± 4.8
Overweight or obeseb (%) 479 (73.7) 786 (75.4) 769 (74.2) 470 (80.2) 163 (84.0) 190 (90.0) 88 (88.9) 83 (92.2)
Average systolic BP, mmHg (mean) 128.7 ± 18.1 128.4 ± 18.2 127.2 ± 17.9 128.3 ± 18.3 129.1 ± 17.8 134.2 ± 18.6 132.5 ± 19.1 134.5 ± 18.1
Average diastolic BP, mmHg (mean) 76.7 ± 10.0 76.4 ± 10.0 75.9 ± 9.8 76.2 ± 10.0 76.6 ± 10.1 79.2 ± 11.0 76.3 ± 9.9 77.0 ± 9.1
Hypertensionc (%) 280 (43.0) 472 (45.3) 455 (43.8) 301 (51.4) 109 (56.2) 135 (64.0) 72 (72.7) 66 (73.3)
Triglycerides, mmol/l (median) 1.1 (0.8─1.4) 1.1 (0.8─1.5) 1.1 (0.8–1.4) 1.1 (0.9–1.5) 1.2 (0.9─1.6) 1.3 (1.0–1.8) 1.6 (1.1–2.2) 1.7 (1.1–2.3)
High triglyceridesd (%) 110 (17.3) 168 (16.5) 155 (15.3) 98 (17.1) 40 (21.1) 56 (27.5) 44 (45.8) 43 (49.4)
HDL-C, mmol/l (mean) 1.51 ± 0.4 1.50 ± 0.4 1.51 ± 0.4 1.46 ± 0.4 1.41 ± 0.3 1.34 ± 0.4 1.20 ± 0.4 1.19 ± 0.4
Low HDL-Ce (%) 89 (14.0) 157 (15.4) 148 (14.6) 103 (18.0) 35 (18.4) 55 (27.0) 49 (51.0) 41 (47.1)
HbA1c, mmol/mol (median) 36.0 (35.0─37.0) 38.0 (36.0─39.0) 38.0 (36.0─40.0) 40.0 (39.0─42.0) 43.0 (42.0─44.0) 41.0 (38.0─43.0) 57.0 (50.0─69.0) 57.0 (49.0─69.0)
FPG, mmol/l (median) 4.9 (4.6─5.2) 5.0 (4.7─5.3) 4.9 (4.7─5.2) 5.2 (4.8─5.5) 5.4 (5.1─5.9) 5.9 (5.7─6.2) 8.0 (6.8─9.1) 8.4 (7.6─9.6)

Number and (%) are shown for dichotomous variables; DASH score, BMI, systolic BP, diastolic BP and HDL-C are shown as a mean (± one standard deviation). Age, triglycerides, HbA1c and FPG are shown as a median (interquartile range). Numbers and % may vary as some variables have missing values.

aBottom 40% DASH score.

bBMI ≥25.

cSystolic BP ≥140 or diastolic BP ≥90 or on anti-hypertensive medications.

dTriglycerides ≥1.7.

eHDL-C <1.03 males or <1.29 females.