Table 2. Factors associated with pre-diabetes and type 2 diabetes according to diagnosis by HbA1c or FPG.
Variable | Odds ratio (95% CI) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Pre-diabetes compared to normoglycaemia | Type 2 diabetes compared to normoglycaemia | |||||||||||
HbA1c ADA | P | HbA1c WHO-IEC | P | FPG ADA | P | HbA1c ADA | P | HbA1c WHO-IEC | P | FPG ADA | P | |
Male | 0.80 (0.64–0.99) | .045 | 1.03 (0.76─1.40) | .861 | 1.98 (1.46─2.69) | < .001 | 1.96 (1.25–3.07) | .003 | 2.20 (1.42─3.41) | < .001 | 2.45 (1.55─3.87) | < .001 |
Age ≥65 years | 1.38 (1.10–1.74) | .006 | 1.62 (1.17─2.23) | .004 | 1.52 (1.12─2.07) | .008 | 2.60 (1.60–4.23) | < .001 | 2.41 (1.50─3.87) | < .001 | 2.63 (1.59─4.37) | < .001 |
Married or cohabiting | 0.81 (0.62–1.07) | .138 | 0.63 (0.45─0.89) | .009 | 0.65 (0.47─0.91) | .013 | 0.93 (0.56–1.57) | .796 | 0.95 (0.58─1.58) | .853 | 0.84 (0.50–1.40) | .496 |
Health rating, very good or good | 0.60 (0.43–0.84) | .003 | 0.75 (0.49─1.15) | .188 | 0.54 (0.37─0.79) | .001 | 0.27 (0.16–0.44) | < .001 | 0.33 (0.21─0.52) | < .001 | 0.32 (0.20─0.52) | < .001 |
Primary education only | 1.26 (0.96–1.65) | .1 | 1.24 (0.87─1.79) | .239 | 1.61 (1.15–2.26) | .005 | 2.04 (1.27–3.28) | .003 | 1.89 (1.20─2.99) | .006 | 2.29 (1.42–3.68) | .001 |
Current smoker | 1.67 (1.11─2.50) | .014 | 0.96 (0.55─1.67) | .887 | 1.05 (0.63–1.77) | .849 | 1.58 (0.77–3.26) | .215 | 1.20 (0.60─2.39) | .6 | 1.18 (0.57–2.43) | .652 |
High alcohol intake | 0.86 (0.56–1.33) | .5 | 1.35 (0.75─2.43) | .324 | 1.73 (1.04–2.88) | .034 | 0.27 (0.07–1.15) | .076 | 0.30 (0.07─1.27) | .1 | 0.77 (0.27–2.21) | .632 |
Low-level physical activity | 1.21 (0.95–1.55) | .132 | 0.85 (0.61─1.18) | .325 | 0.97 (0.70–1.34) | .841 | 1.08 (0.68–1.71) | .752 | 0.96 (0.61─1.51) | .861 | 0.99 (0.62–1.59) | .969 |
Poor diet qualitya | 1.24 (0.99–1.56) | .061 | 1.34 (0.98─1.82) | .063 | 1.64 (1.22–2.21) | .001 | 1.66 (1.08–2.57) | .022 | 1.57 (1.03─2.40) | .037 | 1.80 (1.15–2.82) | .01 |
Overweight or obeseb | 1.45 (1.11–1.89) | .007 | 1.71 (1.14─2.58) | .01 | 3.15 (1.97–5.05) | < .001 | 2.86 (1.49–5.47) | .002 | 2.61 (1.37─4.95) | .003 | 4.13 (1.89–9.05) | < .001 |
Hypertensionc | 1.40 (1.12–1.75) | .003 | 1.55 (1.14─2.11) | .005 | 2.28 (1.68–3.09) | < .001 | 3.53 (2.21–5.65) | < .001 | 3.23 (2.04─5.10) | < .001 | 3.52 (2.17–5.71) | < .001 |
High triglyceridesd | 0.99 (0.73–1.33) | .93 | 1.35 (0.92─1.98) | .13 | 2.10 (1.48–2.99) | < .001 | 4.04 (2.57–6.34) | < .001 | 4.28 (2.77─6.60) | < .001 | 5.43 (3.45–8.55) | < .001 |
Low HDL-Ce | 1.35 (0.99–1.84) | .059 | 1.24 (0.83─1.85) | .3 | 2.17 (1.52–3.09) | < .001 | 6.40 (4.04–10.12) | < .001 | 5.71 (3.70─8.82) | < .001 | 5.23 (3.31–8.24) | < .001 |
Univariate multinomial logistic regression.
aBottom 40% DASH score.
bBMI ≥25.
cSystolic BP ≥140 or diastolic BP ≥90 or on anti-hypertensive medications.
dTriglycerides ≥1.7.
eHDL-C <1.03 males or <1.29 females.