Table 1.
Comparison of baseline clinical and biochemical characteristics
| Variables | Mean (SD) | P | |
|---|---|---|---|
| Group-1 (MND-ALS) (n=30) | Group-2 (Controls) (n=33) | ||
| Age (years) | 59.2 (7.1) | 61.2 (5.9) | 0.125 |
| BMI (kg/m2) | 23.5 (3.7) | 24.1 (2.1) | 0.531 |
| Waist hip ratio | 0.98 (0.04) | 0.98 (0.05) | 0.982 |
| Albumin corrected Calcium (mg/dL) | 9.4 (0.5) | 9.6 (0.4) | 0.258 |
| Serum phosphorus (mg/dL) | 3.7 (0.5) | 3.5 (0.4) | 0.409 |
| Serum albumin (g/dL) | 4.5 (0.3) | 4.6 (0.3) | 0.126 |
| Serum alkaline phosphatase (U/L) | 75.3 (22.8) | 89.5 (22.8) | 0.052 |
| Creatinine (mg/dL) | 0.71 (0.1) | 0.83 (0.1) | 0.058 |
| 25 hydroxy Vitamin-D (ng/mL) | 28.5 (11.6) | 33.6 (11.6) | 0.075 |
| Parathyroid Hormone (pg/mL) | 47.7 (16.6) | 53.1 (22.0) | 0.417 |
| CTx* (pg/mL) | 698.9 (309.5) | 401.1 (158.7) | <0.001 |
| P1NP* (ng/mL) | 64.3 (40.0) | 47.1 (16.0) | 0.030 |
| Testosterone (ng/dL) | 402.5 (192) | 390.1 (99) | 0.755 |
*CTx – C-terminal telopeptideof type 1 collagen; PINP – Procollagen type 1 N-terminal propeptide