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Therapeutic index. The therapeutic index (TI) is defined as toxic dose (TD50)/effective dose (EC50).
| Toxic Dose (TD50) | Effective Dose (ED50) | Therapeutic Index (TI) | |
|---|---|---|---|
| Ribavirin | 1,306,801 µM | 2.647 μM | 4.9 × 105 |
| Favipiravir (T-705) | 16,796 µM | 3.888 μM | 4.3 × 103 |
