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. 2021 Jun 15;13(6):424. doi: 10.3390/toxins13060424

Figure 6.

Figure 6

Compounds 211, 224, 270, 271, and 343 are as effective as tamoxifen (TAM) in inhibiting retrograde trafficking of STx2B. (A). STx2B transport assay after exposure to DMSO (0.1%) or 10 µM indicated compounds for 24 h. Cells were fixed at 0 or 60 min after the start of transport. Scale bars, 25 µm. (B,C). Quantification of STx2B signal from (A). DMSO-treated cells at 0 min normalized to 100. N ≥ 25 cells per condition. * p < 0.05 by one-way ANOVA and Tukey–Kramer post hoc test for indicated comparisons; n.s., not significant.