Table 1.
Demographics and plasma levels of pGSN, FGF-21, and GDF-15 in the sample study.
| Patient | MD (n = 60) | Non-MD (n = 41) | Control (n = 56) | p-Value | |
|---|---|---|---|---|---|
| Age, mean (SD) | 46.8 (15.8) | 48.0 (18.1) | 50.1 (19.5) | 0.61 | |
| Gender | F | 38 (63%) | 21 (51%) | 31 (55%) | 0.45 |
| M | 22 (37%) | 20 (49%) | 25 (45%) | ||
|
pGSN, median
[p25, p75] |
143.0 [102.1; 335.7] |
240.0 [120.4; 375.5] |
399.0 [338.0; 515.3] |
<0.001 | |
| FGF21, median [p25, p75] |
353.1 [198.9; 588.0] |
100.5 [34.2; 219.0] |
154.4 [98.1; 254.9] |
<0.001 | |
|
GDF15, median
[p25, p75] |
1777.0 [800.9; 2292.0] |
550.6 [361.9; 1061.6] |
546.4 [376.7; 761.1] |
<0.001 |
M: Male; F: Female; MD: mitochondrial disease; non-MD: non-mitochondrial disease; Control: healthy subjects. Median (P50), 25th percentile (P25) and 75th percentile (P75) are indicated.