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DNA methylation in female versus male bovine in vivo- or in vitro-derived blastocysts. (A) Global CpG methylation values for sexed blastocyst in each group. (B) PCA for individual blastocysts. F and M suffixes in the blastocyst ID label the sex (F: female; M: male). (C) PCA for samples split by culture group and sex (sub-groups). (D) Correlation coefficient between each subgroup. (E) Hierarchical clustering by subgroups.
