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. 2021 Jun 15;13(12):3006. doi: 10.3390/cancers13123006

Figure 2.

Figure 2

miRNA expression in serum exosomes at different time points in Stable and Progressed patients. miR-21 (A), -222 (B) and -124-3p (C) expression in serum exosomes was measured by real-time qPCR with TaqMan probes and normalized to U6 snRNA. Data are expressed as Log2FC. Comparisons between Stable and Progressed patients at each time point were analyzed with non-parametric U Mann–Whitney test. Differences were considered statistically significant as p < 0.05 (*), p < 0.01 (**), and p < 0.001 (***). Median miR-21 (D), -222 (E) and -124-3p (F) expression level in serum exosomes of Stable and Progressed patients was reported at each time point. Variations of miRNA expression levels at different time points were evaluated by ANOVA. Differences were considered statistically significant as p < 0.05 (*), p < 0.01 (**), and p < 0.001 (***).