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. 2021 Jun 15;10(6):1501. doi: 10.3390/cells10061501

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© 2021 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Diffusion artifact (II). Top panels: Albumin (a) and IgG (b) immunoreactivities in hepatocellular carcinoma metastatic to the hepatic hilar lymph node. Bottom panels: IgA immunostaining in normal (c) and neoplastic (d) thyroid. Hepatocellular carcinoma cells, normal thyroid follicular cells, and papillary thyroid carcinoma cells reveal diffuse cytoplasmic staining for the plasma proteins (albumin, IgG, and IgA) in some cells. The nuclei remain negative. The Golgi area of plasma cells is immunoreactive for IgG in panel (b). The nuclei are counterstained with methyl green.