Table 2.
IC50 values (µg/mL) for the activities of crude extracts against 10 human cancer MCF-7, A427, RT-4, SiSo, LCLC-103H, DAN-G, A2780, KYSE-70, HL-60, U-937 cell lines, and PBMC.
| Cell Lines | Mean ± Standard Error of Mean (µg/mL) | |||
|---|---|---|---|---|
| A. schimperi | E. schimperiana | K. petitiana | K. foliosa | |
| A427 | 2.17 ± 0.41 | 1.85 ± 0.44 | 2.09 ± 0.43 | 14.54 ± 4.14 |
| MCF-7 | 10.31 ± 3.45 | Nd | 10.41 ± 5.59 | 14.89 ± 2.38 |
| RT-4 | 5.18 ± 0.69 | 2.13 ± 3.78 | 6.83 ± 0.79 | 17.3 ± 5.44 |
| SiSo | 2.86 ± 0.29 | 3.28 ± 1.2 | 3.79 ± 0.49 | 17.8 ± 2.31 |
| LCLC-103H | 3.06 ± 0.3 | 0.086 | 7.33 ± 2.7 | 24.16 ± 0.4 |
| DAN-G | 5.23 ± 1.7 | Nd | 9.6 ± 1.6 | 27.06 ± 10.8 |
| KYSE-70 | 2.87 ± 0.3 | 30.37 | 3.45 ± 1.6 | 22.03 ± 3.4 |
| A2780 | 1.87 ± 0.4 | 26.54 ± 18.5 | 2.35 ± 0.9 | 16.77 ± 4.6 |
| HL-60 | 4.08 ± 1.4 | Nd | 8.0 ± 1.7 | 24.2 ± 0.3 |
| U-937 | 9.76 ± 6.8 | 47.68 | 8.58 ± 3.5 | 16.9 |
| PBMC | ˃50 | ˃50 | ˃50 | ˃50 |
Testing was conducted with the crystal violet assay except for the HL-60 and U937 cell lines, which were tested with the MTT assay. All values are averages with a standard error of mean of three independent experiments; Nd (not determined).