Table 2.

Predictors of composite end-point (in-hospital mortality or admission to ICU) and in-hospital mortality (risk estimates by Cox's regression).

Variables	Composite end-point Model p < .001, Harrell's C = 0.68		Mortality Model p < .001, Harrell's C = 0.75
	HR (95%CI)	P-value	HR (95%CI)	P-value
Female gender	0.84 (0.69–1.02)	0.086	0.92 (0.72–1.18)	0.51
Age ≥70 years	2.37 (1.79–3.14)	<0.001	5.20 (3.97–6.82)	<0.001
Body mass index (kg/m2) <20.0 20.0–24.9 25.0–29.9 ≥30.0	0.97 (0.63–1.49) 1 (reference) 1.10 (0.81–1.49) 1.20 (0.98–1.48)	0.37 0.89 0.56 0.079	0.91 (0.51–1.62) 1 (reference) 1.02 (0.66–1.59) 0.98 (0.75–1.27)	0.97 0.75 0.91 0.86
Weight loss in the previous month No Yes Unknown	1 (reference) 0.68 (0.31–1.49) 0.84 (0.37–1.92)	0.54 0.34 0.69	1 (reference) 0.79 (0.36–1.74) 0.92 (0.40–2.11)	0.82 0.57 0.85
Reduced food intake No Self-reported before or expected after admission Self-reported before & expected after admission	1 (reference) 2.24 (1.42–3.54) 3.21 (2.14–4.81)	<0.001 0.001 <0.001	1 (reference) 1.97 (1.25–3.11) 3.20 (1.90–5.38)	<0.001 0.004 <0.001
Number of comorbidities >2	1.33 (1.02–1.73)	0.033	1.75 (1.36–2.25)	<0.001

Abbreviations: HR, hazard ratio; 95%CI, 95% confidence interval.