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Germinal Center structure after ChAdOx1 nCoV-19 immunization
Representative immunofluorescence of sections from spleens of 3-month-old (A) and 22-month-old (B) ChAdOx1 nCoV-19 immunized mice. Left side shows typical field of view of four channels and right side shows 2D composite image during a germinal center acquisition. The scale bars represent 50 μm. IgD+ B cell follicle in green, CD3+ T cells in magenta, Ki67+ cells in blue and CD35+ follicular dendritic cells in white.
